The Food and Drug Administration, FDA, has approved the drug Vivitrol for that treatment of opioid dependence based on a news release by them on 10-12-2010. Using two separate drugs to lose weight naturally can be very effective there are combinations before the FDA now awaiting approval. When dealing with fat loss and the people that go through it you ought to err to the side of caution and allow the FDA do its job and demand some investigation be done so the public is aware of the side effects and dangers of the medications before we take them. Keep in mind that drug companies come in business to make money and that they would say almost anything to keep people on the medications. Researchers found that participants using this drug to get a year, dropped excess weight within 4 weeks and have kept the extra weight off through the entire 56 weeks with the study. Contrave is really a combination of the drugs naltrexone and bupropion, which usually reflect a whole new trend of weight-loss drugs that are made up of more than one active ingredient, that might make them more effective and safer. Combo-pilling will be the newest fad or also the newest into the future under scrutiny and thus it is just more publicly known recently, comb-pilling to lose weight has been around since the eighties. The biggest reason that employing a combination of pills is starting to become popular could be the fact that since right now there aren't any long term prescription diet pills that have been approved by the FDA besides orlistat. The truly disturbing part is doctors are prescribing these combinations of medications however some of the combinations have been rejected or have yet to be approved by the FDA. Seizures are a side effect with Contrave and shouldn't be taken in individuals with seizure disorders. The drug can also raise blood pressure levels and heart rate, and shouldn't be used in people with a history of heart attack or stroke in the previous six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy using the drug. The FDA also warned that Contrave can raise blood pressure level and heart rate and must not be used in patients with uncontrolled high hypertension, along with by anyone with heart-related and cerebrovascular (circulation system dysfunction impacting your brain) disease. Patients which has a history of cardiac event or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded from your clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes using a boxed warning to alert medical researchers and patients towards the increased probability of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for stop smoking. An independent report published by Gant Daily in April also stated that naltrexone also utilizes kleptomaniacs and gambling addicts, as well. Citing research in the University of Minnesota School of Medicine, Gant Daily reported the drug conditions kleptomaniacs and chronic gamblers just as with alcohol and opioid addicts'by blocking the effects of endorphins, which the brain releases when experiencing craving or compulsions.